Architecture-Dependent Noise Discriminates Functionally Analogous Differentiation Circuits
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چکیده
منابع مشابه
Architecture-Dependent Noise Discriminates Functionally Analogous Differentiation Circuits
Gene regulatory circuits with different architectures (patterns of regulatory interactions) can generate similar dynamics. This raises the question of why a particular circuit architecture is selected to implement a given cellular process. To investigate this problem, we compared the Bacillus subtilis circuit that regulates differentiation into the competence state to an engineered circuit with...
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ژورنال
عنوان ژورنال: Cell
سال: 2009
ISSN: 0092-8674
DOI: 10.1016/j.cell.2009.07.046